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Doxepin Pharmacodynamics: Indication or Adverse Effect?
Doxepin is a tricyclic antidepressant first approved for the treatment of depression in 1969 by the FDA. Tricyclic antidepressants are famous for their anticholinergic adverse effects including...
Indication Guides Dosing – Primidone and Escitalopram
There are numerous examples of where the indication guides dosing. It is important as a pharmacist to remember this when you see unusual doses. I wanted to share a couple of examples that I came...
Medications That Interfere With Continuous Glucose Monitoring
Technology continues to impact disease state management in remarkable ways. Monitoring of patients with diabetes is no exception. Both the American Diabetes Association and American Association of...
Cyclobenzaprine And The Prescribing Cascade
Cyclobenzaprine (podcast episode) is a skeletal muscle relaxant that is most commonly used for muscle spasms and back pain. It definitely has some potential adverse effects that I have seen lead to...
Top 5 CYP2C19 Drug Interactions
Here's a list of some of the most common CYP2C19 drug interactions that I have seen in clinical practice. Citalopram and Omeprazole Interaction Omeprazole can significantly increase the...
Ziprasidone With Or Without Food?
Here's a case scenario where the clinical outcome may have hinged on taking ziprasidone with or without food. KD is a 33-year-old male who was diagnosed with schizophrenia. Olanzapine and...
SSRIs and CYP Enzymes
While many who don't understand pharmacology consider the SSRIs to be interchangeable, significant consequences can result if we don't pay attention to the risk of drug interactions. When looking at...
Constipation Prescribing Cascade
At its worst, constipation can be a very serious issue in some patients and at best be a significant nuisance. Here's a classic example of the constipation prescribing cascade. A 72-year-old female...
BCPS Recertification By Exam Pros and Cons
Many have asked me what are the pros and cons of doing BCPS recertification by exam. Here are my thoughts on this. BCPS Recertification by Exam: The Pros If you are anything like me, I learn best...
Tramadol Drug Interactions
Tramadol is used in clinical practice, but it does have numerous drug interactions that you should be aware of. When reviewing a medication list or when a patient starts a new medication, here are...
Study Materials For Pharmacists
