While we often think about bacterial infections and managing the use of antibiotics, fungal and viral infections are relatively common in practice as well. We have many antifungal medications, and we also have a large number of antiviral agents. When comparing fungal...
Fluconazole is a commonly used antifungal agent with strong CYP450 inhibitory activity, especially on the CYP2C9, CYP2C19, and CYP3A4 enzymes. Because of this, it can significantly affect the metabolism of many medications. Here are my top five fluconazole drug...
Azole antifungals play a central role in the treatment and prevention of fungal infections, offering coverage against yeasts, molds, and dimorphic fungi depending on the agent. Each drug in this class comes with its own specific spectrum and set of indications. In a...
When treating herpes simplex virus (HSV) or varicella-zoster virus (VZV), two antiviral agents commonly used are acyclovir and valacyclovir. While both medications are effective, understanding their pharmacokinetic profiles, dosage forms, and clinical uses can help...
Azole antifungals are known for treating various types of yeast, molds, and dimorphic fungi, however, their safety profiles significantly vary, especially when it comes to hepatotoxicity, QT prolongation, and gastrointestinal (GI) effects. We will break down and...
Fluoroquinolones are broad-spectrum antibiotics used to treat a wide variety of bacterial infections. However, they have a long list of medication interactions that require careful consideration when prescribing and counseling. In this blog post, I will highlight my...
