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Cytisinicline – New Option in Smoking Cessation on the Horizon?
Cytisinicline is a naturally occurring plant-based alkaloid compound that is derived from laburnum and cytisus. It has been commercially available over the counter in Europe for decades. This...
Can You Pass? NSAID Crossword Puzzle
If you're a pharmacist or pharmacy student looking to test your knowledge of nonsteroidal anti-inflammatory drugs (NSAIDs), we've got the perfect brain-teasing activity for you. Introducing our...
Fungal Versus Viral Infections – 2 Key Differences
While we often think about bacterial infections and managing the use of antibiotics, fungal and viral infections are relatively common in practice as well. We have many antifungal medications, and...
Top 5 Fluconazole Drug Interactions
Fluconazole is a commonly used antifungal agent with strong CYP450 inhibitory activity, especially on the CYP2C9, CYP2C19, and CYP3A4 enzymes. Because of this, it can significantly affect the...
Venlafaxine Versus Desvenlafaxine
When comparing venlafaxine versus desvenlafaxine, we must first recognize that they are both part of the drug class called SNRIs. Both of these medications work by inhibiting the reuptake of both...
Top 5 NSAID Drug Interactions Every Pharmacist Should Know
Nonsteroidal anti-inflammatory drugs (NSAIDs) are routinely used for pain and inflammation, but they are also commonly implicated in clinically significant interactions. As medication experts,...
Top 5 Drug Interactions in Rheumatoid Arthritis
Rheumatoid arthritis (RA) often requires complex, long-term medication regimens. This polypharmacy increases the risk of clinically significant drug interactions that can impact efficacy and safety....
Sulfonylureas with Insulin – Case Scenario
One of my biggest pet peeves is the use of sulfonylureas with insulin. Recall that sulfonylureas stimulate the release of insulin and in many patients with Type 2 diabetes we may not be getting much...
Top 5 Bactrim Drug Interactions
Trimethoprim-sulfamethoxazole (Bactrim) is a commonly prescribed antibiotic for urinary tract and other infections. However, it’s also associated with several clinically significant drug...
Losartan Differences – A Deep Dive on ARBs
Angiotensin II receptor blockers (ARBs) are widely used in managing hypertension, heart failure, chronic kidney disease (CKD), and diabetic nephropathy. While these agents share a common...