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Change Your Mindset – Reduce Meds
One of the biggest contributors to polypharmacy isn’t the number of diagnoses a patient has—it’s our mindset around medications that fail to deliver benefit. Everyone knows we need to reduce meds in...
Diabetes Polypharmacy – 3 Case Examples
Prescribing cascades don’t usually start with “bad” medications. In fact, they often begin with some of our most effective therapies. Metformin, SGLT2 inhibitors, and GLP-1 receptor agonists all...
PPIs and Metformin Leads to Deficiency – Case Study
In this case scenario, we discuss the "double trouble" of using PPIs and metformin and their effects on vitamin B12. Mrs. J is a 68-year-old woman with type 2 diabetes and gastroesophageal reflux...
Top 5 Gout Pharmacotherapy Pearls
In this blog post, I'll share my top 5 gout pharmacotherapy pearls. This can often show up in practice as well as on those challenging board exams! Allopurinol Doesn't Treat Flares Allopurinol...
Deprescribing Targets – Case Scenario
Mr. H is a 78-year-old male presenting to a primary care clinic for a routine medication review. In this scenario, we want to identify deprescribing targets. His past medical history includes...
Paxlovid Alprazolam Interaction – Case Scenario
In this case scenario, we outline the Paxlovid alprazolam interaction. A 42-year-old woman with a long-standing history of severe generalized anxiety disorder, managed with alprazolam 1 mg orally...
Pimavanserin Practice Pearls
Pimavanserin is a unique antipsychotic with a very specific niche in clinical practice. It is most commonly used for Parkinson's disease psychosis, and its pharmacology, benefits, and risks are...
Top 5 Testable Pearls – Alpha Blockers
Alpha-blockers are not first-line agents for many conditions, but they are often tested on exams and highly relevant in practice—especially in urology, hypertension, and acute care settings....
Biotin Causes Thyroid Problems
In this case scenario, we outline a situation where biotin causes thyroid problems. It highlights the importance of recognizing the use of OTC and supplement medications. A 46-year-old woman with a...
Medications That Cause Hypersexuality
As I’m sure many of us who commonly work with elderly patients in nursing homes have seen, patients can experience hypersexuality and exhibit behaviors that put themselves and other residents at...











