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Duplicate Antidepressant Therapy – Sertraline and Duloxetine
In this case scenario, I review a common situation I've encountered with duplicate antidepressant therapy. JS is a 67-year-old male with a history of type 2 diabetes, peripheral neuropathy, and...
Apixaban Dose Adjustment and Bleeding Risk
In this case scenario, we will look at the importance of making an apixaban (podcast) dose adjustment based upon clinical factors. LS is an 83-year-old female with a history of atrial fibrillation,...
Pramipexole and Drug Induced Hypersexuality – Case Study
ES is a 74-year-old female with mild dementia managed with donepezil 10 mg nightly. She had been experiencing severe nighttime restlessness and an irresistible urge to move her legs, leading to...
Adding Metolazone to Furosemide – Don’t Forget to Check Labs!
SK is a 74-year-old male with a history of chronic systolic heart failure, hypertension, and type 2 diabetes. He has been stable on a regimen that includes carvedilol, sacubitril/valsartan,...
Should We Discontinue a PPI in Hospice?
I was asked a question the other day about trying to reduce medications in a patient on hospice. More specifically, how to address the use of PPIs. Proton pump inhibitors (PPIs) are some of the most...
Midodrine Prescribing Cascade and Complications – Case Study
In this case study, we will outline an adverse effect of midodrine that can lead to the prescribing cascade. SK is a 79-year-old male nursing home resident with a history of Parkinson’s disease,...
Top 10 Meds That Induce Seizures
When working with patients who have a seizure disorder, it’s critical for pharmacists to remember which medications can lower the seizure threshold. Even in patients without epilepsy, some drugs can...
Why Isn’t Iron Replacement Working? My Top 4 Reasons
Oral iron replacement is one of the most common ways to manage iron deficiency anemia. While it seems straightforward—take a pill, replace the iron—patients often struggle to reach therapeutic...
Can You Identify Two Important Drug Interactions? Case Study
SK is a 77-year-old male who presents to the primary care clinic for a routine follow-up. His past medical history is significant for atrial fibrillation, hypertension, GERD, and depression. Can you...
A Rundown of Vitamin D Dosing
What is Vitamin D? Vitamin D is a fat-soluble vitamin that our body makes when the skin is exposed to sunlight. It is also found in certain foods like fish, dairy, and eggs. Vitamin D helps the body...