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A Free Sample of My Biggest Project to Date!

I’ve been working over the last six months or so on a condensed BCPS study guide.  As always, I will be given a substantial discount upon release of the new book, so stayed tuned in the next month or two.  It will be over 150 topics and give you the most important clinical pearls from those topics.  It is going to end up being well over 300 pages!!!!  A few other pharmacists and myself are working on the proofing/editing at this time.  I’m also thinking about what to title the book.  Here’s what I am thinking so far.

“BCPS Bullets: The Distilled BCPS Study Guide” or do you like

“BCPS Bullets: The Condensed BCPS Study Guide”

If you have any other good ideas as to a title, I would be all ears!

Here’s a sample topic of what to expect –

Hyperparathyroidism

Signs/Symptoms/Diagnosis/Complications

  • Parathyroid hormone is released from the parathyroid gland
  • Hormone that aids in calcium and phosphorus homeostasis
  • High parathyroid hormone causes higher calcium levels and lower phosphorus levels
  • Low parathyroid hormone can cause higher phosphorus levels and lower calcium levels
  • Secondary hyperparathyroidism is common in kidney failure
  • Hyperparathyroidism increases risk of osteoporosis, kidney stones
  • Kidney failure
    • Inability or reduced ability to convert vitamin D to most active form
    • Causes a drop in calcium level
    • Drop in calcium stimulates PTH production and possible inappropriate elevation
  • Maintaining calcium phosphorus is very important
  • Elevated serum calcium can contribute to increased cardiovascular risks

Common risk factors

  • Females
  • Lithium use

Medications to Know

  • Calcimimetics
    • Cinacalcet
    • Reduces parathyroid hormone by “mimicking” calcium in the negative feedback loop
      • Remember that high calcium levels will cause reduced parathyroid hormone via negative feedback
    • Incredibly important to monitor calcium and phosphorus
    • Side effects
      • Low BP, parathesias fatigue, GI, Anemia
    • 3A4 Inhibitors may increase concentration of this drug
    • Very expensive
  • Vitamin D analogs
    • Stimulates calcium preservation
    • Increase in calcium levels from vitamin D will cause a reduction in parathyroid hormone production and release
    • Vitamin D also can increase phosphorus levels
    • Monitoring of calcium/phosphorus is important
  • Bisphosphonates
    • Can help reduce loss of calcium out of bones
    • Protection of osteoporosis
    • See osteoporosis for more information
  • Phosphate Binders
    • Critical for patients who have higher phosphorus levels
    • See dialysis for more information

If you have any comments or questions, please leave a comment below! Thanks,

Eric

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Written By Eric Christianson

February 15, 2017

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