by Eric Christianson | Feb 25, 2026 | Cardiovascular Medication and Disease State Clinical Pearls
When a patient presents with dizziness, falls, or orthostatic symptoms, antihypertensives and diuretics often get the blame first. However, many non–blood pressure medications can lower blood pressure through a variety of mechanisms. Failing to recognize these...
by Eric Christianson | Apr 2, 2025 | Neurology, Pain, and Musculoskeletal Medication and Disease State Clinical Pearls
Sinemet, a key medication for managing Parkinson’s disease, combines carbidopa and levodopa to improve motor symptoms such as tremors, stiffness, and slow movement. However, Sinemet is known for its potential drug interactions, which can affect its efficacy and lead...
by Eric Christianson | Feb 21, 2024 | Neurology, Pain, and Musculoskeletal Medication and Disease State Clinical Pearls
I have been caught in situations with caregivers and patients numerous times regarding Parkinson’s medication management. Patients can be VERY particular about getting their Parkinson’s medication on time. This is understandable if you acknowledge what...
by Eric Christianson | Jun 19, 2022 | Uncategorized
Carbidopa/levodopa (Sinemet) is used for managing motor symptoms of Parkinson’s Disease (PD). Levodopa is a dopamine precursor used to replenish depleted dopamine levels associated with PD. Unfortunately, levodopa isn’t effective alone as it is broken down before...
by Eric Christianson | Feb 24, 2021 | Medication and Disease State Clinical Pearls For Pharmacists, Neurology, Pain, and Musculoskeletal Medication and Disease State Clinical Pearls
Parkinson’s disease (PD) has long presented challenges in medication delivery. A staple in more advanced disease control, carbidopa-levodopa requires multiple daily dosing with supratherapeutic levels leading to dyskinesias and subtherapeutic concentrations leading to...
