by Eric Christianson | Feb 18, 2026 | Cardiovascular Medication and Disease State Clinical Pearls
Thiazide and thiazide-like diuretics remain foundational therapies in hypertension management. Two of the most commonly discussed agents are hydrochlorothiazide (HCTZ) and chlorthalidone. While they are often used interchangeably in practice, important pharmacologic...
by Eric Christianson | Feb 11, 2026 | Cardiovascular Medication and Disease State Clinical Pearls
Fibrates are lipid-lowering agents that are primarily used to reduce triglycerides. They are most beneficial in patients with significantly elevated triglyceride levels, particularly those above 500 mg/dL, where the primary clinical goal is reducing the risk of...
by Eric Christianson | Feb 8, 2026 | Neurology, Pain, and Musculoskeletal Medication and Disease State Clinical Pearls
Oral bisphosphonates (i.e., alendronate) are commonly used to treat osteoporosis, and proper administration is one of the most important concepts for the NAPLEX exam. These medications must be taken first thing in the morning on an empty stomach with a full glass of...
by Eric Christianson | Feb 4, 2026 | Cardiovascular Medication and Disease State Clinical Pearls
Rhabdomyolysis happens when muscle cells break down and release their contents into the blood. These substances can damage the kidneys and cause serious problems like kidney failure. It is often triggered by medications, injuries, extreme exercise, or drug...
by Eric Christianson | Jan 11, 2026 | Neurology, Pain, and Musculoskeletal Medication and Disease State Clinical Pearls
In this blog post, I’ll share my top 5 gout pharmacotherapy pearls. This can often show up in practice as well as on those challenging board exams! Allopurinol Doesn’t Treat Flares Allopurinol reduces the production of uric acid. Because of this mechanism,...
by Eric Christianson | Dec 31, 2025 | Psychiatry and Addiction Medication and Disease State Clinical Pearls
Pimavanserin is a unique antipsychotic with a very specific niche in clinical practice. It is most commonly used for Parkinson’s disease psychosis, and its pharmacology, benefits, and risks are frequently tested and clinically misunderstood. In this blog post,...
