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Case Scenario: Duplicate SNRI Therapy
This was a case I came across recently where duloxetine was added to a patient's regimen. The provider did not adequately assess the medication and recognize that the patient was already taking an...
Propranolol-Induced Asthma – Case Study
In this case study, we outline a likely case of propranolol-induced asthma. Mr. J.S. is a 62-year-old male with a past medical history significant for essential tremor, mild persistent asthma,...
Change Your Mindset – Reduce Meds
One of the biggest contributors to polypharmacy isn’t the number of diagnoses a patient has—it’s our mindset around medications that fail to deliver benefit. Everyone knows we need to reduce meds in...
Diabetes Polypharmacy – 3 Case Examples
Prescribing cascades don’t usually start with “bad” medications. In fact, they often begin with some of our most effective therapies. Metformin, SGLT2 inhibitors, and GLP-1 receptor agonists all...
PPIs and Metformin Leads to Deficiency – Case Study
In this case scenario, we discuss the "double trouble" of using PPIs and metformin and their effects on vitamin B12. Mrs. J is a 68-year-old woman with type 2 diabetes and gastroesophageal reflux...
Top 5 Gout Pharmacotherapy Pearls
In this blog post, I'll share my top 5 gout pharmacotherapy pearls. This can often show up in practice as well as on those challenging board exams! Allopurinol Doesn't Treat Flares Allopurinol...
Deprescribing Targets – Case Scenario
Mr. H is a 78-year-old male presenting to a primary care clinic for a routine medication review. In this scenario, we want to identify deprescribing targets. His past medical history includes...
Paxlovid Alprazolam Interaction – Case Scenario
In this case scenario, we outline the Paxlovid alprazolam interaction. A 42-year-old woman with a long-standing history of severe generalized anxiety disorder, managed with alprazolam 1 mg orally...
Pimavanserin Practice Pearls
Pimavanserin is a unique antipsychotic with a very specific niche in clinical practice. It is most commonly used for Parkinson's disease psychosis, and its pharmacology, benefits, and risks are...
Top 5 Testable Pearls – Alpha Blockers
Alpha-blockers are not first-line agents for many conditions, but they are often tested on exams and highly relevant in practice—especially in urology, hypertension, and acute care settings....











