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Acyclovir Versus Valacyclovir – What’s the Difference?

Acyclovir Versus Valacyclovir – What’s the Difference?

by Eric Christianson | May 7, 2025 | Infectious Disease and Oncology Medication and Disease State Clinical Pearls

When treating herpes simplex virus (HSV) or varicella-zoster virus (VZV), two antiviral agents commonly used are acyclovir and valacyclovir. While both medications are effective, understanding their pharmacokinetic profiles, dosage forms, and clinical uses can help...
Oral Lorazepam PRN For A Seizure? Is This Right?

Oral Lorazepam PRN For A Seizure? Is This Right?

by Eric Christianson | Jan 22, 2025 | Neurology, Pain, and Musculoskeletal Case Studies

Do you ever get those questions where you know you are correct but you have to check the literature? I believe I’ve come across this order once or twice in my career: oral lorazepam PRN for a seizure. Can this be done? Here are the details on why this...
Carbamazepine Auto-Induction And What To Do About It

Carbamazepine Auto-Induction And What To Do About It

by Eric Christianson | Aug 4, 2024 | Neurology, Pain, and Musculoskeletal Medication and Disease State Clinical Pearls

Carbamazepine auto-induction is a popular Board Exam question and is a term I learned in pharmacy school but I never remember being taught what that means clinically and how to monitor the auto-induction period effectively. Indications Matter I want to discuss...
New GERD Medication – Vonoprazan for Erosive Esophagitis

New GERD Medication – Vonoprazan for Erosive Esophagitis

by Eric Christianson | May 12, 2024 | Clinical Pharmacy News and New Drug Updates, Gastrointestinal Medication and Disease State Clinical Pearls

On November 1, 2023, the U.S. Food and Drug Administration (FDA) approved VOQUEZNA® (vonoprazan) as a new treatment for the healing and maintenance of erosive esophagitis and the relief of heartburn associated with erosive esophagitis in adults. This FDA approval...
Sleep Or Depression? Trazodone’s Dose Dependent Clinical Response

Sleep Or Depression? Trazodone’s Dose Dependent Clinical Response

by Eric Christianson | Apr 17, 2024 | Psychiatry and Addiction Medication and Disease State Clinical Pearls

Trazodone belongs to a class of drugs called serotonin antagonist and reuptake inhibitors (SARIs). Although trazodone is only FDA-approved for the treatment of major depressive disorder (MDD), it is most often used off-label to manage insomnia. What’s interesting...
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Enjoy the blog?  Over 6,000 pharmacy loving folks follow the blog, why aren't you? Subscribe now and get a free gift as well!

Recent Posts

  • Acyclovir Versus Valacyclovir – What’s the Difference?
  • Prescribing Cascade in Dementia Care – My Top 5
  • Comparing Azole Adverse Effects
  • Recommendations in Long Term Care – 5 Recent Examples
  • Prednisone Clinical Pearls – My Top 5

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