There are numerous types of drug interactions. I outline some of the most common ways that drugs can affect the concentrations and activity of other drugs. Opposing Effects Many drugs will work on various receptors throughout the body. To use as an educational point,...
Metformin is the go-to first-line medication in type 2 diabetes. While drug interactions aren’t incredibly common with its use, we should be aware of OCT inhibition and the potential effects that this might cause. Under normal circumstances, this isn’t...
In the case scenario below, I discuss the implications of the verapamil phenytoin interaction. JS is a 38-year-old male who has been on phenytoin for seizure prophylaxis for several years. He reports to his primary care provider complaining of severe headaches. He is...
When the NOACs (sometimes referred to as DOACs) first came out they were heavily promoted as having fewer drug interactions compared to warfarin. This is true, but please remember that “fewer drug interactions” doesn’t mean “no drug...
A 62-year-old male had a heart attack about 9 months ago. He was stented and placed on both aspirin 81 mg daily and clopidogrel 75 mg daily. He presents today to the emergency department and is diagnosed with a STEMI. His wife is wondering why the medications used to...
