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OCD Versus Depression – SSRI Dosing

OCD Versus Depression – SSRI Dosing

by Eric Christianson | Apr 1, 2026 | Psychiatry and Addiction Medication and Disease State Clinical Pearls

SSRIs are the drug of choice for many conditions. That is true of both obsessive-compulsive disorder and depression (excellent board exam nugget to remember). As you are reviewing a patient’s medication list or potentially helping with that patient’s...
Venlafaxine Versus Desvenlafaxine

Venlafaxine Versus Desvenlafaxine

by Eric Christianson | Jun 25, 2025 | Psychiatry and Addiction Medication and Disease State Clinical Pearls

When comparing venlafaxine versus desvenlafaxine, we must first recognize that they are both part of the drug class called SNRIs. Both of these medications work by inhibiting the reuptake of both serotonin and norepinephrine. Venlafaxine comes in an extended-release...
SSRI Clinical Pearls – My Top 5

SSRI Clinical Pearls – My Top 5

by Eric Christianson | Sep 8, 2024 | Psychiatry and Addiction Medication and Disease State Clinical Pearls

In this blog post, I want to share some important SSRI clinical pearls that help clinicians decide which of these antidepressants to use. Note that these clinical practice pearls are good examples of some testable items that may show up on your board exam 🙂 Sertraline...
Tramadol and Fluoxetine Interaction

Tramadol and Fluoxetine Interaction

by Eric Christianson | Sep 4, 2024 | Psychiatry and Addiction Medicine Case Studies

JS is a 58-year-old female who has taken tramadol (podcast) for years due to chronic back pain. She has been experiencing worsening symptoms of depression and has been tried on duloxetine and sertraline in the past. Both of these medications caused GI upset and she is...
What Is Bad About Paroxetine – 3 Strikes and You’re Out

What Is Bad About Paroxetine – 3 Strikes and You’re Out

by Eric Christianson | Jul 21, 2024 | Psychiatry and Addiction Medication and Disease State Clinical Pearls

Paroxetine is from the family of SSRIs (selective serotonin reuptake inhibitors. It has been around for a long time and is indicated for depression, anxiety, and many other psychiatric indications just like other SSRIs. It doesn’t get much love from healthcare...
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Enjoy the blog?  Over 6,000 pharmacy loving folks follow the blog, why aren't you? Subscribe now and get a free gift as well!

Recent Posts

  • If I Had 60 Seconds to Review a Med List, Here’s What I Would Do…
  • Why “Stable” Leads to Polypharmacy – 3 Case Examples
  • Clonidine Versus Guanfacine – Comparison in ADHD
  • 5 Reasons To Get Rid Of PRNs
  • Bowel Regimens – Curbing Polypharmacy

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