Selective Serotonin Reuptake Inhibitors are a mainstay in the management of depression and other mental health disorders. All SSRIs are not created equal and when I am reviewing a patient case, I make sure to look for specific things that may put a patient at risk for...
In this case scenario, I explore some of the possible reasons that you may see a patient on duplicate SSRIs. A 68 year old female has a history of depression, breast cancer, diabetes, hypertension, and mild osteoarthritis. Current medications include: Fluoxetine 20 mg...
If you are a healthcare professional, inevitably, questions about the use of antidepressants in pregnancy come up in clinical practice. Why is paroxetine generally avoided in pregnancy? The primary reason that paroxetine is avoided in pregnancy is that it has...
As I’m working on 2020 updates for all of our board certification study material, I couldn’t help but recognize that I did not have a dedicated lecture on pharmacogenomics. Below I discuss how genetic alterations in CYP2D6 activity can affect two commonly...
The SSRI and NSAID interaction kind of drives me crazy. It is one of those interactions where you don’t really know how seriously to take it. SSRI has the potential to impact platelet function. NSAIDs have the potential to impact platelet function. The SSRI and...
