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Tapering Benzodiazepines – Tricks of the Trade

Tapering Benzodiazepines – Tricks of the Trade

by Eric Christianson | Mar 8, 2020 | Medication and Disease State Clinical Pearls For Pharmacists, Psychiatry and Addiction Medication and Disease State Clinical Pearls

Tapering benzodiazepines or any drug for that matter is a bit of an art. Sure we do have some evidence on these types of topics, but we can’t also schedule a taper schedule perfectly based upon a percentage of the dose. Dosage forms and the patients themselves...
Comparing Lorazepam and Diazepam

Comparing Lorazepam and Diazepam

by Eric Christianson | Sep 1, 2019 | Medication and Disease State Clinical Pearls For Pharmacists, Psychiatry and Addiction Medication and Disease State Clinical Pearls

Benzodiazepines are on the Beers criteria. They can have significant adverse effects like sedation, confusion, the risk for dependence, and increased fall risk. We like to avoid benzodiazepines if we can, but what if we do feel that it is necessary (i.e. hospice or...
5 Anticholinergic Medications Used for Unique Indications

5 Anticholinergic Medications Used for Unique Indications

by Eric Christianson | Jul 24, 2019 | Medication and Disease State Clinical Pearls For Pharmacists, Psychiatry and Addiction Medication and Disease State Clinical Pearls

There are dozens of medications that have anticholinergic activity or are considered an anticholinergic medication. While most of the agents are used for their antihistamine, sedative, or antidepressant activity, There are a few uses that are unique to individual...
Clozapine’s Boxed Warnings – Can You Name All Five?

Clozapine’s Boxed Warnings – Can You Name All Five?

by Eric Christianson | May 22, 2019 | Medication and Disease State Clinical Pearls For Pharmacists, Psychiatry and Addiction Medication and Disease State Clinical Pearls

I was recently reviewing some clinical pearls on clozapine and was really surprised that there were five boxed warnings! After reading them over, I did recall all of the potential negative adverse effects that this drug can cause but did not remember that they were...
SSRI Platelet Inhibition – Clinical Relevance

SSRI Platelet Inhibition – Clinical Relevance

by Eric Christianson | Oct 17, 2018 | Medication and Disease State Clinical Pearls For Pharmacists, Psychiatry and Addiction Medication and Disease State Clinical Pearls

I’ve covered many potential adverse effects and clinical quirks with the SSRI’s on this podcast, but one mystery still remains.  What to do about the SSRI platelet inhibition effect?  The SSRI platelet inhibition effect is a real clinical conundrum.  If...
Tricyclic Antidepressants – Clinical Practice Pearls

Tricyclic Antidepressants – Clinical Practice Pearls

by Eric Christianson | Sep 19, 2018 | Medication and Disease State Clinical Pearls For Pharmacists, Psychiatry and Addiction Medication and Disease State Clinical Pearls

The tricyclic antidepressants are often overlooked as they do have some real negative adverse effects and potential drug interactions.  I’ll give you 5 important clinical pearls below when considering using the tricyclic antidepressants. Know Thy Indication....
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