by Eric Christianson | Feb 3, 2021 | Medication and Disease State Clinical Pearls For Pharmacists, Psychiatry and Addiction Medication and Disease State Clinical Pearls
Here’s a case scenario where the clinical outcome may have hinged on taking ziprasidone with or without food. KD is a 33-year-old male who was diagnosed with schizophrenia. Olanzapine and risperidone were the first antipsychotics that were tried to help...
by Eric Christianson | Jan 27, 2021 | Drug Interaction Case Studies and Education For Pharmacists, Medication and Disease State Clinical Pearls For Pharmacists, Psychiatry and Addiction Medication and Disease State Clinical Pearls
While many who don’t understand pharmacology consider the SSRIs to be interchangeable, significant consequences can result if we don’t pay attention to the risk of drug interactions. When looking at the SSRIs and CYP enzymes, it is critical to remember...
by Eric Christianson | Jan 6, 2021 | Medication and Disease State Clinical Pearls For Pharmacists, Psychiatry and Addiction Medication and Disease State Clinical Pearls
Looking at the adverse effect profile of second-generation antipsychotics is critical to medication selection in clinical practice. You should definitely know the general list of adverse effects of antipsychotics (i.e. EPS, metabolic syndrome, QTc prolongation, etc.)....
by Eric Christianson | Sep 30, 2020 | Medication and Disease State Clinical Pearls For Pharmacists, Psychiatry and Addiction Medication and Disease State Clinical Pearls
In this case scenario, I explore some of the possible reasons that you may see a patient on duplicate SSRIs. A 68 year old female has a history of depression, breast cancer, diabetes, hypertension, and mild osteoarthritis. Current medications include: Fluoxetine 20 mg...
by Eric Christianson | Aug 19, 2020 | Medication and Disease State Clinical Pearls For Pharmacists, Psychiatry and Addiction Medication and Disease State Clinical Pearls
As previously discussed, mirtazapine can be more sedating at lower doses. Mirtazapine has a high affinity for the H1 (histamine) receptor. This histamine blockade is thought to increase appetite and sedation. Weight gain with mirtazapine can be advantageous or a...
by Eric Christianson | Aug 9, 2020 | Medication and Disease State Clinical Pearls For Pharmacists, Psychiatry and Addiction Medication and Disease State Clinical Pearls
Mirtazapine is commonly used in elderly patients with depression who are also suffering from insomnia. Mirtazapine is often chosen because it is much safer than benzodiazepines, “z-drugs”, and antipsychotics. The mechanisms of mirtazapine (podcast episode on the...