by Eric Christianson | Jul 27, 2025 | Women’s and Men’s Health Medication and Disease State Clinical Pearls
Benign prostatic hyperplasia (BPH) is one of those conditions that creeps up with age and quietly causes a whole bunch of problems—especially when medications make it worse. A patient might come in complaining of frequent urination, a weak stream, or feeling like they...
by Eric Christianson | Jul 20, 2025 | Cardiovascular Medication and Disease State Clinical Pearls
Direct oral anticoagulants (DOACs) are widely used in a variety of conditions, including atrial fibrillation, pulmonary embolism, and deep vein thrombosis. Most DOACs are metabolized by CYP3A4 and utilize the P-glycoprotein (P-gp) transporter. Thus, common...
by Eric Christianson | Jul 13, 2025 | Renal, Urology, and Electrolytes Medication and Disease State Clinical Pearls
In this blog post, we will compare tamsulosin versus alfuzosin. Tamsulosin and alfuzosin both act on the sympathetic nervous system. Tamsulosin and alfuzosin both work as Alpha1 antagonists. More specifically, tamsulosin targets the Alpha1A receptor subtype. Both...
by Eric Christianson | Jul 6, 2025 | Neurology, Pain, and Musculoskeletal Medication and Disease State Clinical Pearls
If you’re a pharmacist or pharmacy student looking to test your knowledge of nonsteroidal anti-inflammatory drugs (NSAIDs), we’ve got the perfect brain-teasing activity for you. Introducing our NSAID Crossword Puzzle—a fun, interactive way to review key...
by Eric Christianson | Jul 2, 2025 | Infectious Disease and Oncology Medication and Disease State Clinical Pearls
While we often think about bacterial infections and managing the use of antibiotics, fungal and viral infections are relatively common in practice as well. We have many antifungal medications, and we also have a large number of antiviral agents. When comparing fungal...
by Eric Christianson | Jun 29, 2025 | Infectious Disease and Oncology Medication and Disease State Clinical Pearls
Fluconazole is a commonly used antifungal agent with strong CYP450 inhibitory activity, especially on the CYP2C9, CYP2C19, and CYP3A4 enzymes. Because of this, it can significantly affect the metabolism of many medications. Here are my top five fluconazole drug...
