GLP-1 agonists are an effective medication in treating type 2 diabetes mellitus. GLP-1 agonists are a synthetic version of the body’s naturally occurring GLP-1. However, synthetic GLP-1 has the advantage of being resistant to DPP4 degradation. GLP-1 agonists have...
Parkinson’s disease can be very debilitating and not understanding how medications should be dosed can compound the problem. Let’s review the pharmacology briefly and why you need to be careful with Sinemet 10/100. In Parkinson’s, we have a dopamine...
If you are a healthcare professional, inevitably, questions about the use of antidepressants in pregnancy come up in clinical practice. Why is paroxetine generally avoided in pregnancy? The primary reason that paroxetine is avoided in pregnancy is that it has...
Timolol is an effective medication for reducing intraocular pressure in patients with glaucoma. The recommended starting dose is one drop of timolol 0.25% ophthalmic solution in the affected eye(s) twice daily. It is a non-selective beta-blocker. Ophthalmic...
As previously discussed, mirtazapine can be more sedating at lower doses. Mirtazapine has a high affinity for the H1 (histamine) receptor. This histamine blockade is thought to increase appetite and sedation. Weight gain with mirtazapine can be advantageous or a...
Many providers will not encounter patients with HIV very often, but it may become more commonplace now as HIV therapy has improved dramatically as well as life expectancy in patients with the disease. It is important for providers to meet these patients’ HIV-related...