by Eric Christianson | Oct 22, 2025 | Infectious Disease and Oncology Medication and Disease State Clinical Pearls
UTI prophylaxis is a relatively common occurance in geriatrics and long term care. Antibiotic use on a chronic basis comes with some challenges and mistakes can absolutely happen. More meds, more problems. Making sure chronic antibiotics are safe and effective is an...
by Eric Christianson | Aug 3, 2025 | Infectious Disease and Oncology Medication and Disease State Clinical Pearls
Many infectious diseases are more prevalent in other areas of the world. In this article, we will cover three important travel diseases along with their prophylaxis and treatment recommendations that may show up on your board exam. Malaria Malaria is caused by the...
by Eric Christianson | Jul 2, 2025 | Infectious Disease and Oncology Medication and Disease State Clinical Pearls
While we often think about bacterial infections and managing the use of antibiotics, fungal and viral infections are relatively common in practice as well. We have many antifungal medications, and we also have a large number of antiviral agents. When comparing fungal...
by Eric Christianson | Jun 29, 2025 | Infectious Disease and Oncology Medication and Disease State Clinical Pearls
Fluconazole is a commonly used antifungal agent with strong CYP450 inhibitory activity, especially on the CYP2C9, CYP2C19, and CYP3A4 enzymes. Because of this, it can significantly affect the metabolism of many medications. Here are my top five fluconazole drug...
by Eric Christianson | May 11, 2025 | Infectious Disease and Oncology Medication and Disease State Clinical Pearls
Azole antifungals play a central role in the treatment and prevention of fungal infections, offering coverage against yeasts, molds, and dimorphic fungi depending on the agent. Each drug in this class comes with its own specific spectrum and set of indications. In a...
by Eric Christianson | May 7, 2025 | Infectious Disease and Oncology Medication and Disease State Clinical Pearls
When treating herpes simplex virus (HSV) or varicella-zoster virus (VZV), two antiviral agents commonly used are acyclovir and valacyclovir. While both medications are effective, understanding their pharmacokinetic profiles, dosage forms, and clinical uses can help...