by Eric Christianson | Aug 25, 2019 | Drug Interaction Case Studies and Education For Pharmacists
As I’m working on 2020 updates for all of our board certification study material, I couldn’t help but recognize that I did not have a dedicated lecture on pharmacogenomics. Below I discuss how genetic alterations in CYP2D6 activity can affect two commonly...
by Eric Christianson | Aug 14, 2019 | Drug Interaction Case Studies and Education For Pharmacists
Enzyme inducers most frequently reduce the concentrations of other drugs. This can ultimately lead to treatment failure. In rare situations (i.e. prodrugs), starting an enzyme inducer can potentially raise concentrations of the active metabolite and increase the risk...
by Eric Christianson | Jul 21, 2019 | Drug Interaction Case Studies and Education For Pharmacists
Phenytoin drug interactions are common in our polypharmacy patient. The key is to monitor patients closely as well as carefully reviewing the medication list when a new medication is going to be started or changed. While there are numerous drug interactions with this...
by Eric Christianson | May 29, 2019 | Drug Interaction Case Studies and Education For Pharmacists
The albuterol beta-blocker interaction is real and is significant. But how significant is it? What questions should you ask yourself? Which Beta-Blocker We Talkin’ Bout? The very first question I would assess is which beta-blocker are we talking about as not all...
by Eric Christianson | May 1, 2019 | Drug Interaction Case Studies and Education For Pharmacists
One of the big advantages of newer agents like rivaroxaban is there’s less potential for diet and drug interactions than with warfarin. Now that doesn’t mean that there aren’t any rivaroxaban drug interactions. We have to pay attention to these...
by Eric Christianson | Apr 21, 2019 | Drug Interaction Case Studies and Education For Pharmacists
In the case scenario below, I outline a case where the Bactrim phenytoin interaction leads to phenytoin toxicity. An 81-year-old female has a history of GERD, OA, and seizures. She hasn’t been feeling the best and reports fatigue and painful urination. She has...