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CYP2D6 – Comparing Paroxetine and Tamoxifen

CYP2D6 – Comparing Paroxetine and Tamoxifen

by Eric Christianson | Aug 25, 2019 | Drug Interaction Case Studies and Education For Pharmacists

As I’m working on 2020 updates for all of our board certification study material, I couldn’t help but recognize that I did not have a dedicated lecture on pharmacogenomics. Below I discuss how genetic alterations in CYP2D6 activity can affect two commonly...
Top 5 Enzyme Inducers You’ll Be Tested On

Top 5 Enzyme Inducers You’ll Be Tested On

by Eric Christianson | Aug 14, 2019 | Drug Interaction Case Studies and Education For Pharmacists

Enzyme inducers most frequently reduce the concentrations of other drugs. This can ultimately lead to treatment failure. In rare situations (i.e. prodrugs), starting an enzyme inducer can potentially raise concentrations of the active metabolite and increase the risk...
Do You Remember These 5 Phenytoin Drug Interactions

Do You Remember These 5 Phenytoin Drug Interactions

by Eric Christianson | Jul 21, 2019 | Drug Interaction Case Studies and Education For Pharmacists

Phenytoin drug interactions are common in our polypharmacy patient. The key is to monitor patients closely as well as carefully reviewing the medication list when a new medication is going to be started or changed. While there are numerous drug interactions with this...
Albuterol Beta-Blocker Interaction – What Should I Do?

Albuterol Beta-Blocker Interaction – What Should I Do?

by Eric Christianson | May 29, 2019 | Drug Interaction Case Studies and Education For Pharmacists

The albuterol beta-blocker interaction is real and is significant. But how significant is it? What questions should you ask yourself? Which Beta-Blocker We Talkin’ Bout? The very first question I would assess is which beta-blocker are we talking about as not all...
Rivaroxaban Drug Interactions – Clinical Impact

Rivaroxaban Drug Interactions – Clinical Impact

by Eric Christianson | May 1, 2019 | Drug Interaction Case Studies and Education For Pharmacists

One of the big advantages of newer agents like rivaroxaban is there’s less potential for diet and drug interactions than with warfarin. Now that doesn’t mean that there aren’t any rivaroxaban drug interactions. We have to pay attention to these...
Bactrim Phenytoin Interaction – Case Study

Bactrim Phenytoin Interaction – Case Study

by Eric Christianson | Apr 21, 2019 | Drug Interaction Case Studies and Education For Pharmacists

In the case scenario below, I outline a case where the Bactrim phenytoin interaction leads to phenytoin toxicity. An 81-year-old female has a history of GERD, OA, and seizures. She hasn’t been feeling the best and reports fatigue and painful urination. She has...
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Enjoy the blog?  Over 6,000 pharmacy loving folks follow the blog, why aren't you? Subscribe now and get a free gift as well!

Recent Posts

  • Fibrates – Practice Pearls and Test Prep
  • Oral Bisphosphonates – NAPLEX Test Prep and Practice Pearls
  • Rhabdomyolysis – 3 Big Things Pharmacists Should Remember
  • Carafate Synthroid Interaction – Leads to Hypothyroidism
  • Case Scenario: Duplicate SNRI Therapy

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