PPIs are well known for their ability to block the release of hydrogen ions into the gut. Because of this, the use of PPIs can lead to a basic environment in the stomach. This is synonymous to have an elevated pH in the stomach. Some oral medications can be...
When most healthcare professionals think about drug interactions, we tend to think about an issue arising when a medication is added to the regimen. A perfect example is the warfarin Bactrim interaction. Here’s a case scenario involving cholestyramine and...
Drug food interactions are common and there can be significant negative consequences from these interactions. A common misconception amongst healthcare professionals who may not have as much experience with drug interactions is that ALL statins interact with...
Avanafil, sildenafil, tadalafil, and vardenafil are PDE-5 inhibitors available in the USA and indicated for erectile dysfunction. PDE-5 inhibitors prevent the breakdown of cGMP and it is also one of the drug classes that interacts with nitrates. Nitrates are one...
Omeprazole is one of the most commonly used medications for heartburn and other GI conditions. In addition to being very commonly prescribed, it is available over-the-counter which allows for widespread use throughout the public without much supervision at times. That...
When considering drug interactions, we may be quick to overlook the food that we eat. Fresh off the release of my latest book Clinician’s Guide to Common Drug Interactions in Primary Care, (Link to Audible Free Book) I lay out my top 5, most clinically...
