The following case on methotrexate and thrombocytopenia was donated by Kirk Seale, M.S., PharmD, BCGP. Kirk received his Master’s degree in Drug regulatory affairs from the University of Florida and received his PharmD from the University of Mississippi. He has also...
A 66-year-old female has a past medical history of diabetes, neuropathy, depression, and hypertension. In this case scenario, I discuss the use of a TCA with an SNRI. Her current medication list includes: Aspirin 81 mg dailyCapsaicin cream prnAmitriptyline 10 mg at...
Benzodiazepines are on the Beers criteria. They can have significant adverse effects like sedation, confusion, the risk for dependence, and increased fall risk. We like to avoid benzodiazepines if we can, but what if we do feel that it is necessary (i.e. hospice or...
Medications and renal failure can go hand in hand. This is of course if we are talking about the right medications. There are numerous medications that can cause an acute renal failure situation, but many times in practice, it is due to a cumulative risk. Here’s...
As I’m working on 2020 updates for all of our board certification study material, I couldn’t help but recognize that I did not have a dedicated lecture on pharmacogenomics. Below I discuss how genetic alterations in CYP2D6 activity can affect two commonly...
