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Digoxin and The Prescribing Cascade

Digoxin and The Prescribing Cascade

by Eric Christianson | May 14, 2025 | Cardiovascular Medication and Disease State Clinical Pearls, Polypharmacy Cases And The Prescribing Cascade

Digoxin is a cardiac glycoside that has a narrow therapeutic window. Because of this, we typically monitor digoxin levels. If levels get too high, we can run into adverse effects. In some cases, particularly geriatric patients, those adverse can be misinterpreted as...
Weight Gain With Mirtazapine – The Heavy Truth

Weight Gain With Mirtazapine – The Heavy Truth

by Eric Christianson | Aug 19, 2020 | Medication and Disease State Clinical Pearls For Pharmacists, Psychiatry and Addiction Medication and Disease State Clinical Pearls

As previously discussed, mirtazapine can be more sedating at lower doses. Mirtazapine has a high affinity for the H1 (histamine) receptor. This histamine blockade is thought to increase appetite and sedation. Weight gain with mirtazapine can be advantageous or a...
Mirtazapine For Insomnia – Are You Using It Correctly?

Mirtazapine For Insomnia – Are You Using It Correctly?

by Eric Christianson | Aug 9, 2020 | Medication and Disease State Clinical Pearls For Pharmacists, Psychiatry and Addiction Medication and Disease State Clinical Pearls

Mirtazapine is commonly used in elderly patients with depression who are also suffering from insomnia. Mirtazapine is often chosen because it is much safer than benzodiazepines, “z-drugs”, and antipsychotics. The mechanisms of mirtazapine (podcast episode on the...

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Subscribe to the Blog!

Enjoy the blog?  Over 6,000 pharmacy loving folks follow the blog, why aren't you? Subscribe now and get a free gift as well!

Recent Posts

  • Fungal Versus Viral Infections – 2 Key Differences
  • Top 5 Fluconazole Drug Interactions
  • Venlafaxine Versus Desvenlafaxine
  • Top 5 NSAID Drug Interactions Every Pharmacist Should Know
  • Top 5 Drug Interactions in Rheumatoid Arthritis

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