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Case Study – Renal Dose Adjustment and Constipation Polypharmacy

Case Study – Renal Dose Adjustment and Constipation Polypharmacy

by Eric Christianson | Aug 10, 2025 | Polypharmacy Cases And The Prescribing Cascade

Mrs. M is an 87-year-old female residing in a skilled nursing facility. Her medication list includes: Apixaban 5 mg BID (for atrial fibrillation) Docusate 100 mg BID Senna 8.6 mg BID PEG 17 g daily Calcium carbonate 500 mg TID Lisinopril 10 mg daily Metoprolol...
Senna and Questran – A Pet Peeve

Senna and Questran – A Pet Peeve

by Eric Christianson | Jul 23, 2025 | Gastrointestinal Case Studies

I think I’ve seen this scenario play out more times than I would like. A patient is prescribed both a laxative, Senna, and Questran (cholestyramine), a medication used to manage diarrhea symptoms. This example of the prescribing cascade often presents slowly...
Constipation Polypharmacy

Constipation Polypharmacy

by Eric Christianson | Jul 3, 2024 | Gastrointestinal Case Studies

JE is a 77-year-old male. He reports significant constipation despite the use of three laxative medications. In this case summary, I will outline the most important medications that can contribute to constipation polypharmacy. Past medical history includes:...
Constipation Management – Reducing Polypharmacy Case Study

Constipation Management – Reducing Polypharmacy Case Study

by Eric Christianson | Mar 30, 2022 | Polypharmacy Cases And The Prescribing Cascade

In the case below, I discuss constipation management and how to reduce polypharmacy by targeting medications that cause this adverse effect. KE is a 77-year-old male with a history of GERD, pruritis, insomnia, low back pain, and recent knee replacement. Constipation...
Constipation Prescribing Cascade

Constipation Prescribing Cascade

by Eric Christianson | Jan 24, 2021 | Polypharmacy Cases And The Prescribing Cascade

At its worst, constipation can be a very serious issue in some patients and at best be a significant nuisance. Here’s a classic example of the constipation prescribing cascade. A 72-year-old female has a history of chronic pain, urinary incontinence,...
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Enjoy the blog?  Over 6,000 pharmacy loving folks follow the blog, why aren't you? Subscribe now and get a free gift as well!

Recent Posts

  • Can You Identify Two Important Drug Interactions? Case Study
  • A Rundown of Vitamin D Dosing
  • Gabapentin and Metolazone – Prescribing Cascade
  • Desmopressin for Urinary Incontinence – Case Study
  • Neuropathy Case Study – A Medication Adverse Effect

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