Bempedoic acid, also known as Nexletol, is a once-daily medication used in patients with increased atherosclerotic cardiovascular disease (ASCVD) or heterozygous familial hypercholesterolemia who are requiring additional LDL-C lowering previously on a maximally...
The Framingham risk score has been the primary method of determining a patient’s 10-year risk of cardiovascular disease. Scores such as this take into account a patient’s specific risk factors including age, gender, systolic blood pressure, total cholesterol,...
Fibrates are a type of amphipathic carboxylic acid that treat hypertriglyceridemia. They work by reducing the liver’s production of VLDL particles that carry triglycerides to tissues and accelerating the body’s removal of triglycerides. Due to this mechanism of...
Ezetimibe (Zetia) is a medication used to lower cholesterol. More specifically, this medication is used in clinical practice to lower LDL and help get patients to a target goal. If you recall from your pharmacology classes, ezetimibe inhibits the absorption of...
As one of the few significant new treatment options approved for reducing the risk of cardiovascular events since statins were approved about 30 years ago, when should icosapent ethyl (Vascepa) actually be used? Icosapent ethyl, sold as Vascepa by Amarin, is a...