Prescribing cascades don’t usually start with “bad” medications. In fact, they often begin with some of our most effective therapies. Metformin, SGLT2 inhibitors, and GLP-1 receptor agonists all have strong outcome data in type 2 diabetes. But when adverse effects are...
A 45-year-old woman with a history of bipolar I disorder was recently hospitalized for a manic episode. Following stabilization, her psychiatrist initiated lithium carbonate at 300 mg twice daily for mood stabilization. Her baseline thyroid function tests were within...
An 82-year-old woman with a history of mild Alzheimer’s dementia is started on donepezil 10 mg nightly to help with memory and cognitive function. After several weeks, her family reports that she’s been waking up multiple times per night to urinate and has complained...
In this case scenario, we will look at the importance of making an apixaban (podcast) dose adjustment based upon clinical factors. LS is an 83-year-old female with a history of atrial fibrillation, hypertension, and osteoarthritis. She’s currently prescribed Eliquis...
ES is a 74-year-old female with mild dementia managed with donepezil 10 mg nightly. She had been experiencing severe nighttime restlessness and an irresistible urge to move her legs, leading to frequent awakenings and fatigue during the day. Her provider diagnosed...