There are dozens of medications that have anticholinergic activity or are considered an anticholinergic medication. While most of the agents are used for their antihistamine, sedative, or antidepressant activity, There are a few uses that are unique to individual...
I was recently reviewing some clinical pearls on clozapine and was really surprised that there were five boxed warnings! After reading them over, I did recall all of the potential negative adverse effects that this drug can cause but did not remember that they were...
I’ve covered many potential adverse effects and clinical quirks with the SSRI’s on this podcast, but one mystery still remains. What to do about the SSRI platelet inhibition effect? The SSRI platelet inhibition effect is a real clinical conundrum. If...
The tricyclic antidepressants are often overlooked as they do have some real negative adverse effects and potential drug interactions. I’ll give you 5 important clinical pearls below when considering using the tricyclic antidepressants. Know Thy Indication....
Jiamin Liau is a clinical pharmacist in Australia who donated this piece on opioid replacement therapy! Ms DF, 27 years old, has been on opioid replacement therapy in the past. Treatment ceased about 20 months ago when she fell pregnant. Stating that she had started...
Antidepressant selection is a bit of an art. There are so many considerations that go into choosing which antidepressant should be utilized. Here’s a few things that I think about where making a recommendation. Pain. The TCA”s and SNRI’s do have...
