by Eric Christianson | May 17, 2026 | Psychiatry and Addiction Medication and Disease State Clinical Pearls
If you follow geriatrics or are board-certified, you probably know that nortriptyline is generally preferred over amitriptyline in this patient population. It’s kind of weird to think there is such a difference because nortriptyline is an active metabolite of...
by Eric Christianson | May 13, 2026 | Psychiatry and Addiction Medication and Disease State Clinical Pearls
Selective serotonin reuptake inhibitors (SSRIs) are among the most frequently prescribed medication classes in clinical practice. While they are generally considered safe and effective, clinicians should remain aware of several important drug interactions that can...
by Eric Christianson | May 10, 2026 | Psychiatry and Addiction Medication and Disease State Clinical Pearls
Seasonal affective disorder (SAD) presents a unique opportunity in psychiatric prescribing because, unlike many other mood disorders, the timing of symptoms is often predictable. Patients typically experience depressive symptoms during the fall and winter months, with...
by Eric Christianson | Apr 29, 2026 | Psychiatry and Addiction Medication and Disease State Clinical Pearls
Clonidine and guanfacine are both alpha-2 adrenergic agonists used in the treatment of ADHD, but they behave differently enough in clinical practice that they are not truly interchangeable. In this article, we will compare and contrast clonidine versus guanfacine in...
by Eric Christianson | Apr 1, 2026 | Psychiatry and Addiction Medication and Disease State Clinical Pearls
SSRIs are the drug of choice for many conditions. That is true of both obsessive-compulsive disorder and depression (excellent board exam nugget to remember). As you are reviewing a patient’s medication list or potentially helping with that patient’s...
by Eric Christianson | Dec 31, 2025 | Psychiatry and Addiction Medication and Disease State Clinical Pearls
Pimavanserin is a unique antipsychotic with a very specific niche in clinical practice. It is most commonly used for Parkinson’s disease psychosis, and its pharmacology, benefits, and risks are frequently tested and clinically misunderstood. In this blog post,...
