Addressing QTc Prolongation drug interactions has always been a challenging topic for me. These drug interactions are really hard to know what to do. Problems arising from these interactions rarely happen, but obviously QTc prolongation can increase the risk of...
There are two major concerns that I think about when it comes to codeine drug interactions and pharmacokinetics. One is pharmacogenetic differences, and the other is the potential for drug interactions. I can’t recall a recommendation or a situation where I...
The cyclobenzaprine and SSRI interaction is usually one that flags on drug interaction programs. I’ll look at a brief scenario and some questions to ponder. A 68 year old female was recently prescribed cyclobenzaprine for neck pain. She is also concurrently...
It’s often difficult to figure out how exactly to proceed in handling drug interactions. In this scenario, I will discuss the lithium and ACE Inhibitor drug interaction. A 48 year old male with a history of bipolar disorder has been recently diagnosed with...
Fluconazole is one of those drugs that has a ton of drug interactions. If you don’t believe me, here’s a classic blast from the past! Here’s a different scenario where I breakdown the fluconazole clopidogrel interaction and some thoughts on how to...
So, what would you say if a patient asked you, “Should I take St. John’s Wort?” My gut screams no! St. John’s Wort is a substantial inducer of many CYP enzymes which can play havoc with many different drugs and their respective levels....
