Doxepin is a tricyclic antidepressant first approved for the treatment of depression in 1969 by the FDA. Tricyclic antidepressants are famous for their anticholinergic adverse effects including sedation and have been replaced by better-tolerated medications as...
There are numerous examples of where the indication guides dosing. It is important as a pharmacist to remember this when you see unusual doses. I wanted to share a couple of examples that I came across recently. Escitalopram When using psychiatric medications, we must...
Technology continues to impact disease state management in remarkable ways. Monitoring of patients with diabetes is no exception. Both the American Diabetes Association and American Association of Clinical Endocrinologists/American College of Endocrinology make light...
Cyclobenzaprine (podcast episode) is a skeletal muscle relaxant that is most commonly used for muscle spasms and back pain. It definitely has some potential adverse effects that I have seen lead to the prescribing cascade. Here’s a rundown of medications that...
Here’s a list of some of the most common CYP2C19 drug interactions that I have seen in clinical practice. Citalopram and Omeprazole Interaction Omeprazole can significantly increase the concentration of citalopram. Because of this drug interaction, there is a...
