by Eric Christianson | Aug 25, 2019 | Drug Interaction Case Studies and Education For Pharmacists
As I’m working on 2020 updates for all of our board certification study material, I couldn’t help but recognize that I did not have a dedicated lecture on pharmacogenomics. Below I discuss how genetic alterations in CYP2D6 activity can affect two commonly...
by Eric Christianson | Aug 21, 2019 | Cardiovascular Medication and Disease State Clinical Pearls, Medication and Disease State Clinical Pearls For Pharmacists
A 62-year-old male had a heart attack about 9 months ago. He was stented and placed on both aspirin 81 mg daily and clopidogrel 75 mg daily. He presents today to the emergency department and is diagnosed with a STEMI. His wife is wondering why the medications used to...
by Eric Christianson | Aug 18, 2019 | Endocrine Medication and Disease State Clinical Pearls, Medication and Disease State Clinical Pearls For Pharmacists
Glucagon can be a lifesaver, literally. Glucagon’s primary use is in the setting of severe hypoglycemia. Glucagon works by increasing cyclic AMP which causes glycogenolysis and gluconeogenesis. This ultimately leads to an increase in glucose in the blood and helps...
by Eric Christianson | Aug 14, 2019 | Drug Interaction Case Studies and Education For Pharmacists
Enzyme inducers most frequently reduce the concentrations of other drugs. This can ultimately lead to treatment failure. In rare situations (i.e. prodrugs), starting an enzyme inducer can potentially raise concentrations of the active metabolite and increase the risk...
by Eric Christianson | Aug 11, 2019 | Polypharmacy Cases And The Prescribing Cascade
In geriatrics, deprescribing has become a very popular term. Deprescribing is simply reducing a patient’s medication burden by reducing and discontinuing medications. This is often done as the potential long term benefits of medication dwindle as a...
