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Digoxin and The Prescribing Cascade

Digoxin and The Prescribing Cascade

by Eric Christianson | May 14, 2025 | Cardiovascular Medication and Disease State Clinical Pearls, Polypharmacy Cases And The Prescribing Cascade

Digoxin is a cardiac glycoside that has a narrow therapeutic window. Because of this, we typically monitor digoxin levels. If levels get too high, we can run into adverse effects. In some cases, particularly geriatric patients, those adverse can be misinterpreted as...
Azole Antifungals Comparison – Indications and Coverage

Azole Antifungals Comparison – Indications and Coverage

by Eric Christianson | May 11, 2025 | Infectious Disease and Oncology Medication and Disease State Clinical Pearls

Azole antifungals play a central role in the treatment and prevention of fungal infections, offering coverage against yeasts, molds, and dimorphic fungi depending on the agent. Each drug in this class comes with its own specific spectrum and set of indications. In a...
Acyclovir Versus Valacyclovir – What’s the Difference?

Acyclovir Versus Valacyclovir – What’s the Difference?

by Eric Christianson | May 7, 2025 | Infectious Disease and Oncology Medication and Disease State Clinical Pearls

When treating herpes simplex virus (HSV) or varicella-zoster virus (VZV), two antiviral agents commonly used are acyclovir and valacyclovir. While both medications are effective, understanding their pharmacokinetic profiles, dosage forms, and clinical uses can help...
Prescribing Cascade in Dementia Care – My Top 5

Prescribing Cascade in Dementia Care – My Top 5

by Eric Christianson | May 4, 2025 | Psychiatry and Addiction Medicine Case Studies

The prescribing cascade occurs when a side effect of a medication is misinterpreted as a new medical condition, leading to the prescription of additional medicines that may be unnecessary and potentially harmful. In patients with dementia, this can be common due to...
Comparing Azole Adverse Effects

Comparing Azole Adverse Effects

by Eric Christianson | Apr 30, 2025 | Infectious Disease and Oncology Medication and Disease State Clinical Pearls

Azole antifungals are known for treating various types of yeast, molds, and dimorphic fungi, however, their safety profiles significantly vary, especially when it comes to hepatotoxicity, QT prolongation, and gastrointestinal (GI) effects. We will break down and...
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Recent Posts

  • UTI Prophylaxis – My Top 5 Practice Pearls
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  • Duplicate Antidepressant Therapy – Sertraline and Duloxetine
  • Apixaban Dose Adjustment and Bleeding Risk
  • Pramipexole and Drug Induced Hypersexuality – Case Study

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