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Clonidine Versus Guanfacine – Comparison in ADHD

Clonidine Versus Guanfacine – Comparison in ADHD

by Eric Christianson | Apr 29, 2026 | Psychiatry and Addiction Medication and Disease State Clinical Pearls

Clonidine and guanfacine are both alpha-2 adrenergic agonists used in the treatment of ADHD, but they behave differently enough in clinical practice that they are not truly interchangeable. In this article, we will compare and contrast clonidine versus guanfacine in...
Clonidine Versus Guanfacine: ADHD Management

Clonidine Versus Guanfacine: ADHD Management

by Eric Christianson | Dec 10, 2023 | Pediatrics Medication and Disease State Clinical Pearls, Psychiatry and Addiction Medication and Disease State Clinical Pearls

This article will discuss two of the three commonly used non-stimulant medications for the management of ADHD and ADHD-related symptoms. We will primarily focus on comparing clonidine versus guanfacine in pediatric patients. As pharmacies deal with shortages of more...

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Subscribe to the Blog!

Enjoy the blog?  Over 6,000 pharmacy loving folks follow the blog, why aren't you? Subscribe now and get a free gift as well!

Recent Posts

  • Why “Stable” Leads to Polypharmacy – 3 Case Examples
  • Clonidine Versus Guanfacine – Comparison in ADHD
  • 5 Reasons To Get Rid Of PRNs
  • Bowel Regimens – Curbing Polypharmacy
  • Beta-Blockers In Asthma; The Best and Worst

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