Angiotensin II receptor blockers (ARBs) are widely used in managing hypertension, heart failure, chronic kidney disease (CKD), and diabetic nephropathy. While these agents share a common mechanism—blocking the angiotensin II type 1 (AT₁) receptor—not all ARBs are...
Thiazide diuretics are commonly are one of the most commonly used classes of antihypertensive agents. They carry many adverse effects. Some can be a nuisance while others can be more serious. In this blog post, I’ll run down the most common thiazide diuretic...
In this hypertension case study, JD is a 64-year-old male who has a history of hypertension, GERD, gout, diabetes, constipation, and sexual dysfunction and presents with the following medication list. Hydrochlorothiazide 25 mg daily Amlodipine 5 mg daily Omeprazole 20...
If you work with patients at all, you’ll see some of the most common antihypertensive agents used on a daily basis. The reason they are used so frequently is because they do not tend to have many significant drug interactions. However, some do exist and I wanted...
Is as needed (PRN) allopurinol appropriate? I have seen as-needed (PRN) orders for allopurinol in practice. It has been rare, but it has happened. Did I like it? No. Allopurinol helps to lower uric acid levels. Allopurinol inhibits xanthine oxidase which is an enzyme...