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3 Common Medications That Can Accumulate In Renal Failure

3 Common Medications That Can Accumulate In Renal Failure

by Eric Christianson | Nov 8, 2026 | Renal, Urology, and Electrolytes Case Studies

Chronic kidney disease (CKD) can significantly impact medication clearance and increase the risk of drug toxicity. Three medications I frequently think about in patients with declining renal function are gabapentin, allopurinol, and digoxin. Here are three case...
Gabapentin and Metolazone – Prescribing Cascade

Gabapentin and Metolazone – Prescribing Cascade

by Eric Christianson | Sep 7, 2025 | Polypharmacy Cases And The Prescribing Cascade

In this case scenario with gabapentin and metolazone, I lay out how the prescribing cascade can rear its ugly head. SK is a 74-year-old male with a past medical history significant for chronic kidney disease stage 3, type 2 diabetes, hypertension, peripheral...
Gabapentin Titration Case Study

Gabapentin Titration Case Study

by Eric Christianson | Jun 19, 2024 | Neurology, Pain, and Musculoskeletal Case Studies

JE is a 75-year-old male with a history of diabetes. He has recently complained of peripheral neuropathy symptoms and his provider has started him on gabapentin 300 mg TID. In this scenario, I’m going to discuss some of the factors to consider when thinking...
RLS Treatment – Clinical Practice Pearls

RLS Treatment – Clinical Practice Pearls

by Eric Christianson | Apr 24, 2024 | Neurology, Pain, and Musculoskeletal Medication and Disease State Clinical Pearls

Restless Legs Syndrome (RLS) can be very debilitating for patients. It is a condition that often warrants pharmacotherapy. But which medications are most effective and how should we choose? I’ll lay out some of the most important RLS treatment clinical pearls in...
Top 5 Reasons To Avoid Gabapentin

Top 5 Reasons To Avoid Gabapentin

by Eric Christianson | Aug 23, 2023 | Neurology, Pain, and Musculoskeletal Medication and Disease State Clinical Pearls

Gabapentin is a frequently used medication for neuropathy, RLS, and various other pain syndromes. In this article, I discuss my top 5 reasons to avoid gabapentin use and pick an alternative. Sedation While the sedative nature of gabapentin can be beneficial when...
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  • 3 Common Medications That Can Accumulate In Renal Failure
  • $100 BCPS All Access Discount + Bonus Freebie! – Time-sensitive!
  • Pharmacology and Pharmacy Exam Tutoring with Eric Christianson, PharmD, BCPS, BCGP
  • Urinary Frequency Case – The Prescribing Cascade
  • Three Sneaky Medications That Cause Hyperkalemia

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Subscribe to the Blog!

Enjoy the blog?  Over 6,000 pharmacy loving folks follow the blog, why aren't you? Subscribe now and get a free gift as well!

Recent Posts

  • 3 Common Medications That Can Accumulate In Renal Failure
  • $100 BCPS All Access Discount + Bonus Freebie! – Time-sensitive!
  • Pharmacology and Pharmacy Exam Tutoring with Eric Christianson, PharmD, BCPS, BCGP
  • Urinary Frequency Case – The Prescribing Cascade
  • Three Sneaky Medications That Cause Hyperkalemia

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