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Top 5 Fluconazole Drug Interactions

Top 5 Fluconazole Drug Interactions

by Eric Christianson | Jun 29, 2025 | Infectious Disease and Oncology Medication and Disease State Clinical Pearls

Fluconazole is a commonly used antifungal agent with strong CYP450 inhibitory activity, especially on the CYP2C9, CYP2C19, and CYP3A4 enzymes. Because of this, it can significantly affect the metabolism of many medications. Here are my top five fluconazole drug...
Azole Antifungals Comparison – Indications and Coverage

Azole Antifungals Comparison – Indications and Coverage

by Eric Christianson | May 11, 2025 | Infectious Disease and Oncology Medication and Disease State Clinical Pearls

Azole antifungals play a central role in the treatment and prevention of fungal infections, offering coverage against yeasts, molds, and dimorphic fungi depending on the agent. Each drug in this class comes with its own specific spectrum and set of indications. In a...
Comparing Azole Adverse Effects

Comparing Azole Adverse Effects

by Eric Christianson | Apr 30, 2025 | Infectious Disease and Oncology Medication and Disease State Clinical Pearls

Azole antifungals are known for treating various types of yeast, molds, and dimorphic fungi, however, their safety profiles significantly vary, especially when it comes to hepatotoxicity, QT prolongation, and gastrointestinal (GI) effects. We will break down and...
Fluconazole Apixaban Interaction

Fluconazole Apixaban Interaction

by Eric Christianson | Jun 26, 2022 | Drug Interaction Case Studies and Education For Pharmacists

Noval oral anticoagulants (NOACs) are non-vitamin K antagonists that include apixaban (pharmacology podcast), dabigatran, rivaroxaban, and edoxaban. NOACs are highly predictable and are less likely to interact with other medications, making them more favorable than...

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Subscribe to the Blog!

Enjoy the blog?  Over 6,000 pharmacy loving folks follow the blog, why aren't you? Subscribe now and get a free gift as well!

Recent Posts

  • Tamsulosin Versus Alfuzosin – What Pharmacists Need to Know
  • Cytisinicline – New Option in Smoking Cessation on the Horizon?
  • Can You Pass? NSAID Crossword Puzzle
  • Fungal Versus Viral Infections – 2 Key Differences
  • Top 5 Fluconazole Drug Interactions

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