by Eric Christianson | Nov 10, 2019 | Drug Interaction Case Studies and Education For Pharmacists, Endocrine Medication and Disease State Clinical Pearls, Medication and Disease State Clinical Pearls For Pharmacists
Metformin is the go-to first-line medication in type 2 diabetes. While drug interactions aren’t incredibly common with its use, we should be aware of OCT inhibition and the potential effects that this might cause. Under normal circumstances, this isn’t...
by Eric Christianson | Nov 6, 2019 | Drug Interaction Case Studies and Education For Pharmacists
In the case scenario below, I discuss the implications of the verapamil phenytoin interaction. JS is a 38-year-old male who has been on phenytoin for seizure prophylaxis for several years. He reports to his primary care provider complaining of severe headaches. He is...
by Eric Christianson | Oct 23, 2019 | Drug Interaction Case Studies and Education For Pharmacists
When the NOACs (sometimes referred to as DOACs) first came out they were heavily promoted as having fewer drug interactions compared to warfarin. This is true, but please remember that “fewer drug interactions” doesn’t mean “no drug...
by Eric Christianson | Aug 21, 2019 | Cardiovascular Medication and Disease State Clinical Pearls, Medication and Disease State Clinical Pearls For Pharmacists
A 62-year-old male had a heart attack about 9 months ago. He was stented and placed on both aspirin 81 mg daily and clopidogrel 75 mg daily. He presents today to the emergency department and is diagnosed with a STEMI. His wife is wondering why the medications used to...
by Eric Christianson | Aug 14, 2019 | Drug Interaction Case Studies and Education For Pharmacists
Enzyme inducers most frequently reduce the concentrations of other drugs. This can ultimately lead to treatment failure. In rare situations (i.e. prodrugs), starting an enzyme inducer can potentially raise concentrations of the active metabolite and increase the risk...
