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Clonidine Versus Guanfacine – Comparison in ADHD

Clonidine Versus Guanfacine – Comparison in ADHD

by Eric Christianson | Apr 29, 2026 | Psychiatry and Addiction Medication and Disease State Clinical Pearls

Clonidine and guanfacine are both alpha-2 adrenergic agonists used in the treatment of ADHD, but they behave differently enough in clinical practice that they are not truly interchangeable. In this article, we will compare and contrast clonidine versus guanfacine in...
Med List Review – Cardiovascular No-No’s

Med List Review – Cardiovascular No-No’s

by Eric Christianson | Mar 24, 2024 | Cardiovascular Case Studies

An 89-year-old female has a history of hypertension, atrial fibrillation, stroke, GERD, osteoporosis, and osteoarthritis. Her current medication list includes the following: Amlodipine (podcast) 5 mg daily Rivaroxaban (podcast) 20 mg daily Clonidine (podcast) 0.2 mg...
Clonidine Versus Guanfacine: ADHD Management

Clonidine Versus Guanfacine: ADHD Management

by Eric Christianson | Dec 10, 2023 | Pediatrics Medication and Disease State Clinical Pearls, Psychiatry and Addiction Medication and Disease State Clinical Pearls

This article will discuss two of the three commonly used non-stimulant medications for the management of ADHD and ADHD-related symptoms. We will primarily focus on comparing clonidine versus guanfacine in pediatric patients. As pharmacies deal with shortages of more...
Tapering Clonidine – Case Study

Tapering Clonidine – Case Study

by Eric Christianson | Aug 1, 2021 | Cardiovascular Case Studies, Educational Case Studies For Pharmacists

In this article, I wanted to share information on tapering clonidine. This drug can cause serious rebound hypertension when abruptly discontinued and patients may not understand or realize that this risk exists. Here’s a case scenario that demonstrates tapering...

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Subscribe to the Blog!

Enjoy the blog?  Over 6,000 pharmacy loving folks follow the blog, why aren't you? Subscribe now and get a free gift as well!

Recent Posts

  • My Top 5 SSRI Drug Interactions
  • Antidepressants in Seasonal Affective Disorder – Which One To Choose?
  • If I Had 60 Seconds to Review a Med List, Here’s What I Would Do…
  • Why “Stable” Leads to Polypharmacy – 3 Case Examples
  • Clonidine Versus Guanfacine – Comparison in ADHD

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