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Should We Discontinue a PPI in Hospice?

Should We Discontinue a PPI in Hospice?

by Eric Christianson | Oct 1, 2025 | Polypharmacy Cases And The Prescribing Cascade

I was asked a question the other day about trying to reduce medications in a patient on hospice. More specifically, how to address the use of PPIs. Proton pump inhibitors (PPIs) are some of the most overused medications we see in clinical practice, but hospice...
Gabapentin and Metolazone – Prescribing Cascade

Gabapentin and Metolazone – Prescribing Cascade

by Eric Christianson | Sep 7, 2025 | Polypharmacy Cases And The Prescribing Cascade

In this case scenario with gabapentin and metolazone, I lay out how the prescribing cascade can rear its ugly head. SK is a 74-year-old male with a past medical history significant for chronic kidney disease stage 3, type 2 diabetes, hypertension, peripheral...
Case Study – Renal Dose Adjustment and Constipation Polypharmacy

Case Study – Renal Dose Adjustment and Constipation Polypharmacy

by Eric Christianson | Aug 10, 2025 | Polypharmacy Cases And The Prescribing Cascade

Mrs. M is an 87-year-old female residing in a skilled nursing facility. Her medication list includes: Apixaban 5 mg BID (for atrial fibrillation) Docusate 100 mg BID Senna 8.6 mg BID PEG 17 g daily Calcium carbonate 500 mg TID Lisinopril 10 mg daily Metoprolol...
Duplicate Antipsychotics In Hospice – Two Real Life Situations

Duplicate Antipsychotics In Hospice – Two Real Life Situations

by Eric Christianson | Aug 6, 2025 | Polypharmacy Cases And The Prescribing Cascade

Here’s a question that comes up in hospice more than you’d think: Why would a hospice patient be on two antipsychotics at the same time? To the average clinician, this raises immediate concerns—duplication, unnecessary side effects, and polypharmacy in a population...
Counteracting Drug Effects: 5 Case Examples I’ve Seen In Practice

Counteracting Drug Effects: 5 Case Examples I’ve Seen In Practice

by Eric Christianson | Jul 16, 2025 | Polypharmacy Cases And The Prescribing Cascade

Counteracting drug effects are all too common in geriatric and polypharmacy patients. I wanted to share common examples that I’ve seen in my practice as a clinical pharmacist. NSAIDs vs. AntihypertensivesCase: A 68-year-old man with hypertension controlled on...
Digoxin and The Prescribing Cascade

Digoxin and The Prescribing Cascade

by Eric Christianson | May 14, 2025 | Cardiovascular Medication and Disease State Clinical Pearls, Polypharmacy Cases And The Prescribing Cascade

Digoxin is a cardiac glycoside that has a narrow therapeutic window. Because of this, we typically monitor digoxin levels. If levels get too high, we can run into adverse effects. In some cases, particularly geriatric patients, those adverse can be misinterpreted as...
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Subscribe to the Blog!

Enjoy the blog?  Over 6,000 pharmacy loving folks follow the blog, why aren't you? Subscribe now and get a free gift as well!

Recent Posts

  • Top 4 Patient Mistakes With Supplements
  • Duplicate Antidepressant Therapy – Sertraline and Duloxetine
  • Apixaban Dose Adjustment and Bleeding Risk
  • Pramipexole and Drug Induced Hypersexuality – Case Study
  • Adding Metolazone to Furosemide – Don’t Forget to Check Labs!

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