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Change Your Mindset – Reduce Meds

Change Your Mindset – Reduce Meds

by Eric Christianson | Jan 21, 2026 | Polypharmacy Cases And The Prescribing Cascade

One of the biggest contributors to polypharmacy isn’t the number of diagnoses a patient has—it’s our mindset around medications that fail to deliver benefit. Everyone knows we need to reduce meds in geriatrics, but how do we do that? Too often, when a drug doesn’t...
Deprescribing Targets – Case Scenario

Deprescribing Targets – Case Scenario

by Eric Christianson | Jan 7, 2026 | Polypharmacy Cases And The Prescribing Cascade

Mr. H is a 78-year-old male presenting to a primary care clinic for a routine medication review. In this scenario, we want to identify deprescribing targets. His past medical history includes hypertension, heart failure with preserved ejection fraction (HFpEF),...
Should We Discontinue a PPI in Hospice?

Should We Discontinue a PPI in Hospice?

by Eric Christianson | Oct 1, 2025 | Polypharmacy Cases And The Prescribing Cascade

I was asked a question the other day about trying to reduce medications in a patient on hospice. More specifically, how to address the use of PPIs. Proton pump inhibitors (PPIs) are some of the most overused medications we see in clinical practice, but hospice...
Gabapentin and Metolazone – Prescribing Cascade

Gabapentin and Metolazone – Prescribing Cascade

by Eric Christianson | Sep 7, 2025 | Polypharmacy Cases And The Prescribing Cascade

In this case scenario with gabapentin and metolazone, I lay out how the prescribing cascade can rear its ugly head. SK is a 74-year-old male with a past medical history significant for chronic kidney disease stage 3, type 2 diabetes, hypertension, peripheral...
Case Study – Renal Dose Adjustment and Constipation Polypharmacy

Case Study – Renal Dose Adjustment and Constipation Polypharmacy

by Eric Christianson | Aug 10, 2025 | Polypharmacy Cases And The Prescribing Cascade

Mrs. M is an 87-year-old female residing in a skilled nursing facility. Her medication list includes: Apixaban 5 mg BID (for atrial fibrillation) Docusate 100 mg BID Senna 8.6 mg BID PEG 17 g daily Calcium carbonate 500 mg TID Lisinopril 10 mg daily Metoprolol...
Duplicate Antipsychotics In Hospice – Two Real Life Situations

Duplicate Antipsychotics In Hospice – Two Real Life Situations

by Eric Christianson | Aug 6, 2025 | Polypharmacy Cases And The Prescribing Cascade

Here’s a question that comes up in hospice more than you’d think: Why would a hospice patient be on two antipsychotics at the same time? To the average clinician, this raises immediate concerns—duplication, unnecessary side effects, and polypharmacy in a population...
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Subscribe to the Blog!

Enjoy the blog?  Over 6,000 pharmacy loving folks follow the blog, why aren't you? Subscribe now and get a free gift as well!

Recent Posts

  • High Dose Antipsychotic Error
  • Fibrates – Practice Pearls and Test Prep
  • Oral Bisphosphonates – NAPLEX Test Prep and Practice Pearls
  • Rhabdomyolysis – 3 Big Things Pharmacists Should Remember
  • Carafate Synthroid Interaction – Leads to Hypothyroidism

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