by Eric Christianson | Jul 16, 2023 | Renal, Urology, and Electrolytes Medication and Disease State Clinical Pearls
Sodium polystyrene sulfonate (SPS, Kayexalate) has been used for decades to help lower potassium levels and manage hyperkalemia. It does this by exchanging sodium ions for potassium ions in the gut (primarily the large intestine). The compound is then removed from the...
by Eric Christianson | Feb 19, 2023 | Renal, Urology, and Electrolytes Medication and Disease State Clinical Pearls
The kidney plays many vital roles in the body. One of those roles is to eliminate medications and their metabolites. When the kidney is not functioning well, drugs are eliminated from the body at a slower rate and can accumulate. Those higher drug concentrations can...
by Eric Christianson | Dec 11, 2022 | Renal, Urology, and Electrolytes Medication and Disease State Clinical Pearls
There are a number of medications that can be used for urge urinary incontinence, also known as “overactive bladder syndrome”. However, it can be somewhat difficult to parse out the differences between the medications and decide which might be the right choice for a...
by Eric Christianson | Aug 4, 2021 | Medication and Disease State Clinical Pearls For Pharmacists, Renal, Urology, and Electrolytes Medication and Disease State Clinical Pearls
Excess calcium levels can be life-threatening if they become severely elevated (>14 mg/dL), causing symptoms such as polyuria and polydipsia due to nephrogenic diabetes insipidus, nephrolithiasis, bone pain, nausea, vomiting, anorexia, confusion, rare cardiac...
by Eric Christianson | Jul 18, 2021 | Medication and Disease State Clinical Pearls For Pharmacists, Renal, Urology, and Electrolytes Medication and Disease State Clinical Pearls
Last week, the FDA approved finerenone (Kerendia) to treat patients with chronic kidney disease (CKD) associated with type 2 diabetes. Finerenone is a nonsteroidal mineralocorticoid receptor antagonist (MRA). The approval of finerenone was due to the results of the...
by Eric Christianson | Jun 2, 2021 | Medication and Disease State Clinical Pearls For Pharmacists, Renal, Urology, and Electrolytes Medication and Disease State Clinical Pearls
There are many medications that falsely raise creatinine. This can be indicative of worsening renal function, but in some situations, it may not be an issue at all. Here’s a case scenario where we look at medications that can falsely raise creatinine by...