Opioids are commonly used in clinical practice. Selection on these agents can often be confusion. We’ve outlined some of the most important pharmacokinetic, pharmacogenomic, and dosage form clinical pearls in the table below. For easier reading, we have also...
Sjogren’s Syndrome is not very common but I do see this diagnosis in practice periodically. This disease has two major symptoms that pharmacists should pay EXTREMELY close attention to. Placing a focus on medications that exacerbate Sjogren’s Syndrome is a...
Acute migraine affects up to 26% of women, and up to 9% of men in the US. It is characterized by a moderate to severe headache that lasts for 4-72 hours and may be unilateral, cause nausea/vomiting, pulsating pain, or photophobia. First-line treatment options include...
Is as needed (PRN) allopurinol appropriate? I have seen as-needed (PRN) orders for allopurinol in practice. It has been rare, but it has happened. Did I like it? No. Allopurinol helps to lower uric acid levels. Allopurinol inhibits xanthine oxidase which is an enzyme...
Benztropine (Cogentin) is an older anticholinergic agent primarily used for movement-type disorders and adverse effects. I’ll share some of my most important benztropine clinical pearls in this article. Benztropine can be used in the management of acute...
Lowering uric acid is the key to reducing gout flares. Both allopurinol (podcast) and febuxostat are effective at performing this task. However, there are some considerations you need to be aware when deciding to utilize allopurinol versus febuxostat. I’ll break...
