I think I’ve seen this scenario play out more times than I would like. A patient is prescribed both a laxative, Senna, and Questran (cholestyramine), a medication used to manage diarrhea symptoms. This example of the prescribing cascade often presents slowly...
Direct oral anticoagulants (DOACs) are widely used in a variety of conditions, including atrial fibrillation, pulmonary embolism, and deep vein thrombosis. Most DOACs are metabolized by CYP3A4 and utilize the P-glycoprotein (P-gp) transporter. Thus, common...
Counteracting drug effects are all too common in geriatric and polypharmacy patients. I wanted to share common examples that I’ve seen in my practice as a clinical pharmacist. NSAIDs vs. AntihypertensivesCase: A 68-year-old man with hypertension controlled on...
In this blog post, we will compare tamsulosin versus alfuzosin. Tamsulosin and alfuzosin both act on the sympathetic nervous system. Tamsulosin and alfuzosin both work as Alpha1 antagonists. More specifically, tamsulosin targets the Alpha1A receptor subtype. Both...
Cytisinicline is a naturally occurring plant-based alkaloid compound that is derived from laburnum and cytisus. It has been commercially available over the counter in Europe for decades. This medication is used as a smoking cessation agent. In the United States, it is...
