by Eric Christianson | Jan 18, 2026 | Endocrine Case Studies
Prescribing cascades don’t usually start with “bad” medications. In fact, they often begin with some of our most effective therapies. Metformin, SGLT2 inhibitors, and GLP-1 receptor agonists all have strong outcome data in type 2 diabetes. But when adverse effects are...
by Eric Christianson | Nov 2, 2025 | Cardiovascular Case Studies
Diuretics are most frequently used for hypertension and to remove excess fluid from the body. The use of diuretics can often cause the prescribing cascade. In this post, I’ll share 3 of my most common examples of diuretics and the prescribing cascade I’ve...
by Eric Christianson | Sep 7, 2025 | Polypharmacy Cases And The Prescribing Cascade
In this case scenario with gabapentin and metolazone, I lay out how the prescribing cascade can rear its ugly head. SK is a 74-year-old male with a past medical history significant for chronic kidney disease stage 3, type 2 diabetes, hypertension, peripheral...
by Eric Christianson | Jul 27, 2025 | Women’s and Men’s Health Medication and Disease State Clinical Pearls
Benign prostatic hyperplasia (BPH) is one of those conditions that creeps up with age and quietly causes a whole bunch of problems—especially when medications make it worse. A patient might come in complaining of frequent urination, a weak stream, or feeling like they...
by Eric Christianson | Jul 23, 2025 | Gastrointestinal Case Studies
I think I’ve seen this scenario play out more times than I would like. A patient is prescribed both a laxative, Senna, and Questran (cholestyramine), a medication used to manage diarrhea symptoms. This example of the prescribing cascade often presents slowly...
