by Eric Christianson | Jun 11, 2025 | Drug Interaction Case Studies and Education For Pharmacists
Trimethoprim-sulfamethoxazole (Bactrim) is a commonly prescribed antibiotic for urinary tract and other infections. However, it’s also associated with several clinically significant drug interactions that can lead to serious patient harm if overlooked. Here are my top...
by Eric Christianson | Aug 21, 2024 | Infectious Disease and Oncology Case Studies
EJ is a 54-year-old female with a history of rheumatoid arthritis. She has been on methotrexate (with folic acid supplementation) for years with relatively few RA flares over the last 10 years. She was recently diagnosed with a urinary tract infection and was...
by Eric Christianson | Jul 30, 2023 | Drug Interaction Case Studies and Education For Pharmacists
After my recent post on my top 5 medication/vitamin interactions, I received the request to cover medications that deplete vitamins and minerals. I loved this idea because it is an important consideration in clinical practice! Keep in mind that these often show up on...
by Eric Christianson | Apr 26, 2023 | Hematology and Immunology Case Studies
I want to address an email from a recent podcast listener regarding the appropriate way to take folic acid with methotrexate. Specifically, what is my take on methotrexate and folic acid same-day dosing? First, let’s start with some basics. Folic Acid (vitamin...
by Eric Christianson | Aug 14, 2022 | Polypharmacy Cases And The Prescribing Cascade
In most clinical situations, I’m a stickler for trying to prevent the prescribing cascade. I lay out hundreds of polypharmacy case examples including the prescribing cascade in my highly rated book Perils of Polypharmacy. The prescribing cascade is simply...
