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Hydrochlorothiazide Versus Chlorthalidone – A Clinical Comparison

Hydrochlorothiazide Versus Chlorthalidone – A Clinical Comparison

by Eric Christianson | Feb 18, 2026 | Cardiovascular Medication and Disease State Clinical Pearls

Thiazide and thiazide-like diuretics remain foundational therapies in hypertension management. Two of the most commonly discussed agents are hydrochlorothiazide (HCTZ) and chlorthalidone. While they are often used interchangeably in practice, important pharmacologic...
Losartan Differences – A Deep Dive on ARBs

Losartan Differences – A Deep Dive on ARBs

by Eric Christianson | Jun 8, 2025 | Cardiovascular Medication and Disease State Clinical Pearls

Angiotensin II receptor blockers (ARBs) are widely used in managing hypertension, heart failure, chronic kidney disease (CKD), and diabetic nephropathy. While these agents share a common mechanism—blocking the angiotensin II type 1 (AT₁) receptor—not all ARBs are...
Hypertension Prescribing Cascade – 3 Common Examples

Hypertension Prescribing Cascade – 3 Common Examples

by Eric Christianson | Dec 15, 2024 | Cardiovascular Case Studies

Hypertension is one of the most common disease states that can lead to an increase in cardiovascular risk and other complications. Because of the risks of elevated blood pressure, we are often forced to use pharmacotherapy to reduce those risks. When a medication is...
Top 5 Thiazide Diuretic Adverse Effects

Top 5 Thiazide Diuretic Adverse Effects

by Eric Christianson | May 19, 2024 | Cardiovascular Medication and Disease State Clinical Pearls

Thiazide diuretics are commonly are one of the most commonly used classes of antihypertensive agents. They carry many adverse effects. Some can be a nuisance while others can be more serious. In this blog post, I’ll run down the most common thiazide diuretic...
Top 5 Antihypertensive Drug Interactions

Top 5 Antihypertensive Drug Interactions

by Eric Christianson | Mar 3, 2024 | Cardiovascular Medication and Disease State Clinical Pearls

Blood pressure medications are commonly used in practice. You should know some of the major interactions with these medications. In this blog post, I will lay out my top 5 antihypertensive drug interactions and also share some information on how these interactions can...
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Enjoy the blog?  Over 6,000 pharmacy loving folks follow the blog, why aren't you? Subscribe now and get a free gift as well!

Recent Posts

  • Licensing 101: Financial Tips Every 4th Year Pharmacy Student Should Know
  • Folate Deficiency – Need to Know Medications
  • Sometimes Less is More: When to De-Escalate Diabetes Medications
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  • Licensing Roadmap Tips Every Pharmacy Student Should Know Before Graduation

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