I don’t recall learning about oxycodone pharmacokinetics in school. Cut me some slack, maybe I was gone that day? Or maybe my memory is fading? It’s actually pretty complicated and drug interactions and pharmacogenomics can play a significant role in how a...
In this article, we break down the most important ketamine clinical pearls. Ketamine (ketamine hydrochloride) is FDA approved for general anesthesia in diagnostic and surgical procedures that do not require skeletal muscle relaxation. It has been used on its own or as...
Opioids are commonly used in clinical practice. Selection on these agents can often be confusion. We’ve outlined some of the most important pharmacokinetic, pharmacogenomic, and dosage form clinical pearls in the table below. For easier reading, we have also...
Sjogren’s Syndrome is not very common but I do see this diagnosis in practice periodically. This disease has two major symptoms that pharmacists should pay EXTREMELY close attention to. Placing a focus on medications that exacerbate Sjogren’s Syndrome is a...
Acute migraine affects up to 26% of women, and up to 9% of men in the US. It is characterized by a moderate to severe headache that lasts for 4-72 hours and may be unilateral, cause nausea/vomiting, pulsating pain, or photophobia. First-line treatment options include...
Is as needed (PRN) allopurinol appropriate? I have seen as-needed (PRN) orders for allopurinol in practice. It has been rare, but it has happened. Did I like it? No. Allopurinol helps to lower uric acid levels. Allopurinol inhibits xanthine oxidase which is an enzyme...
