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Amitriptyline Versus Nortriptyline – What’s The Difference?

Amitriptyline Versus Nortriptyline – What’s The Difference?

by Eric Christianson | May 17, 2026 | Psychiatry and Addiction Medication and Disease State Clinical Pearls

If you follow geriatrics or are board-certified, you probably know that nortriptyline is generally preferred over amitriptyline in this patient population. It’s kind of weird to think there is such a difference because nortriptyline is an active metabolite of...
My Top 5 SSRI Drug Interactions

My Top 5 SSRI Drug Interactions

by Eric Christianson | May 13, 2026 | Psychiatry and Addiction Medication and Disease State Clinical Pearls

Selective serotonin reuptake inhibitors (SSRIs) are among the most frequently prescribed medication classes in clinical practice. While they are generally considered safe and effective, clinicians should remain aware of several important drug interactions that can...
Antidepressants in Seasonal Affective Disorder – Which One To Choose?

Antidepressants in Seasonal Affective Disorder – Which One To Choose?

by Eric Christianson | May 10, 2026 | Psychiatry and Addiction Medication and Disease State Clinical Pearls

Seasonal affective disorder (SAD) presents a unique opportunity in psychiatric prescribing because, unlike many other mood disorders, the timing of symptoms is often predictable. Patients typically experience depressive symptoms during the fall and winter months, with...
Clonidine Versus Guanfacine – Comparison in ADHD

Clonidine Versus Guanfacine – Comparison in ADHD

by Eric Christianson | Apr 29, 2026 | Psychiatry and Addiction Medication and Disease State Clinical Pearls

Clonidine and guanfacine are both alpha-2 adrenergic agonists used in the treatment of ADHD, but they behave differently enough in clinical practice that they are not truly interchangeable. In this article, we will compare and contrast clonidine versus guanfacine in...
Beta-Blockers In Asthma; The Best and Worst

Beta-Blockers In Asthma; The Best and Worst

by Eric Christianson | Apr 19, 2026 | Respiratory Medication and Disease State Clinical Pearls

Beta-blockers have long been approached with caution in patients with asthma due to their potential to provoke bronchospasm and blunt the effects of rescue inhalers. This risk is largely driven by receptor selectivity. In this article, we will break down the best and...
Epoetin 3 Big Things – Practice Pearls and Test Prep

Epoetin 3 Big Things – Practice Pearls and Test Prep

by Eric Christianson | Apr 15, 2026 | Hematology and Immunology Medication and Disease State Clinical Pearls

Epoetin alfa (Epogen/Procrit) is a medication pharmacists commonly encounter in long-term care, dialysis, and oncology settings. While its role in stimulating red blood cell production seems straightforward, there are several key clinical pearls that are essential to...
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  • Amitriptyline Versus Nortriptyline – What’s The Difference?
  • My Top 5 SSRI Drug Interactions
  • Antidepressants in Seasonal Affective Disorder – Which One To Choose?
  • If I Had 60 Seconds to Review a Med List, Here’s What I Would Do…
  • Why “Stable” Leads to Polypharmacy – 3 Case Examples

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Subscribe to the Blog!

Enjoy the blog?  Over 6,000 pharmacy loving folks follow the blog, why aren't you? Subscribe now and get a free gift as well!

Recent Posts

  • Amitriptyline Versus Nortriptyline – What’s The Difference?
  • My Top 5 SSRI Drug Interactions
  • Antidepressants in Seasonal Affective Disorder – Which One To Choose?
  • If I Had 60 Seconds to Review a Med List, Here’s What I Would Do…
  • Why “Stable” Leads to Polypharmacy – 3 Case Examples

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