Nonsteroidal anti-inflammatory drugs (NSAIDs) are routinely used for pain and inflammation, but they are also commonly implicated in clinically significant interactions. As medication experts, pharmacists play a critical role in recognizing and navigating these risks....
Rheumatoid arthritis (RA) often requires complex, long-term medication regimens. This polypharmacy increases the risk of clinically significant drug interactions that can impact efficacy and safety. Below are five of the most important drug interactions encountered in...
One of my biggest pet peeves is the use of sulfonylureas with insulin. Recall that sulfonylureas stimulate the release of insulin and in many patients with Type 2 diabetes we may not be getting much out of the sulfonylurea or in some cases, the extra boost in insulin...
Trimethoprim-sulfamethoxazole (Bactrim) is a commonly prescribed antibiotic for urinary tract and other infections. However, it’s also associated with several clinically significant drug interactions that can lead to serious patient harm if overlooked. Here are my top...
Angiotensin II receptor blockers (ARBs) are widely used in managing hypertension, heart failure, chronic kidney disease (CKD), and diabetic nephropathy. While these agents share a common mechanism—blocking the angiotensin II type 1 (AT₁) receptor—not all ARBs are...
