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Amiodarone is an older antiarrhythmic drug that you may see used in primary care and geriatrics. I’m well into my latest project on a NEW BOOK involving the prescribing cascade and polypharmacy. I wanted to share a part of it by discussing amiodarone adverse effects. Amiodarone adverse effects include things like ocular toxicity, QTc prolongation, […]
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Sacubitril/valsartan (ARNI) is getting more attention in the guidelines with regards to its use in heart failure (specifically HFrEF). Many patients are already on an ACE and making the transition from an ACE inhibitor to an ARNI is likely something you will come across. In clinical practice, there is a significant risk for angioedema when […]
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There are a few important heart failure guideline updates in the works to the American College of Cardiology’s Heart Failure Guidelines, last published in 2013. Prior to the full guideline release, the organization recently printed their updated Expert Consensus Decision Pathway for treatment of patients with heart failure with reduced ejection fraction (HFrEF). This document […]
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Amiodarone is a medication that you need to pay attention to. It has numerous clinical quirks that can cause serious harm if one is not aware of them. Here’s a list of the amiodarone boxed warnings as well as some other clinical practice pearls. Amiodarone Boxed Warning #1: Pro-Arrhythmic Amiodarone is classified as an antiarrhythmic […]
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A 62-year-old male had a heart attack about 9 months ago. He was stented and placed on both aspirin 81 mg daily and clopidogrel 75 mg daily. He presents today to the emergency department and is diagnosed with a STEMI. His wife is wondering why the medications used to prevent this from happening didn’t work. […]
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